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Find hotels in Old Appleton, MO from $67

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    Check prices for these dates, December 12 – 13, 2026

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    Our top choices for Old Appleton hotels

    1. Drury Inn & Suites Jackson MO

    A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

    2. Super 8 by Wyndham Perryville

    A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

    3. Holiday Inn Express & Suites Perryville by IHG

    A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

    4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

    A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a landscaped entrance area.

    5. Tru By Hilton Cape Girardeau

    A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

    6. Comfort Suites Jackson-Cape Girardeau

    A building with a sign reading "Comfort Suites."

    7. Days Inn by Wyndham Perryville

    A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

    8. The Atrium - A Boutique Hotel

    A building with a dark exterior, a large window, and a sign that reads "The Atrium."

    9. Quality Inn Perryville I-55

    A lobby with a TV, framed pictures, a plant, and patterned chairs.

    10. Quality Inn Cape Girardeau North

    A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

    11. Perryville RV Resort

    A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

    12. Town House Inn

    A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

    13. Urban Lofts

    A modern kitchen with a bar area, a dining area with a sofa and chairs, and a large window with curtains.

    14. The Mediterranean House 1858

    A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Old Appleton Hotel Reviews

    Drury Inn & Suites Jackson MO

    A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

    The Atrium - A Boutique Hotel

    A building with a dark exterior, a large window, and a sign that reads "The Atrium."

    La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

    A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a landscaped entrance area.

    Super 8 by Wyndham Perryville

    A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

    Comfort Suites Jackson-Cape Girardeau

    A building with a sign reading "Comfort Suites."

    Urban Lofts

    A modern kitchen with a bar area, a dining area with a sofa and chairs, and a large window with curtains.

    Days Inn by Wyndham Perryville

    A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

    Quality Inn Cape Girardeau North

    A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

    Town House Inn

    A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

    Frequently Asked Questions

    What is the best area to stay in Old Appleton?

    The best area to stay in Old Appleton is within the town center, particularly around the historic district, to fully experience its unique character.

    This area is centered around the Old Appleton Bridge and the Apple Creek, offering a picturesque setting with historical buildings and a relaxed pace. It's a small, walkable community where the main attractions are the natural beauty and the preserved heritage.

    Couples looking for a tranquil escape will find the town center ideal. The quiet surroundings, opportunities for scenic walks along the creek, and the charm of the historic architecture create a great backdrop for a relaxing getaway.

    When is the best time to go to Old Appleton?

    The best time to go to Old Appleton is during the spring or fall when the weather is mild and pleasant for outdoor activities.

    Spring, particularly April and May, brings comfortable temperatures and blooming scenery, making it ideal for exploring the historic sites and natural beauty without the summer heat. This season is superb for couples who enjoy leisurely walks and scenic drives through the countryside.

    Similarly, the fall months of September and October offer crisp air, colorful foliage, and comfortable conditions.

    Can I cancel my hotel reservation on Expedia?

    You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Old Appleton.

    How much is the nightly rate at a Old Appleton hotel?

    Prices for hotels in Old Appleton often vary, but you can find a great deal from $67 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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